Research bibliography
- G.C. Barnard, J.D. McCool, D.W. Wood, and T.U. Gerngross. Integrated recombinant protein expression and purification platform based on Ralstonia eutropha. Applied and Environmental Microbiology, 71(10):5735–5742, 2005.
- G.Q. Chen and Q. Wu. The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials, 26(33):6565–6578, 2005.
- J. Garcia-Ojalvo, M.B. Elowitz, and S.H. Strogatz. Modeling a synthetic multicellular clock: Repressilators coupled by quorum sensing. Proceedings of the National Academy of Sciences, 101(30):10955–10960, July 2004.
- Y. Jia, W. Yuan, J. Wodzinska, C. Park, A.J. Sinskey, and J.A. Stubbe. Mechanistic studies on class I polyhydroxybutyrate(phb) synthase from Ralstonia eutropha: Class I and III synthases share a similar catalytic mechanism. Biochemistry (Washington), 40(4):1011–1019, 2001.
- S.N. Jogdand. BIOPOL - PHB Accumulation in Micro-organisms - General structure & Properties of PHA. Available from World Wide Web: http://members.rediff.com/jogsn/bp6.htm [cited 24 January 2008].
- S.J. Lee, J.P. Park, T.J. Park, S.Y. Lee, S. Lee, and J.K. Park. Selective immobilization of fusion proteins on poly(hydroxyalkanoate) microbeads. Analytical Chemistry, 77(17):5755–5759, 2005.
- S.J. Liu and A. Steinbüchel. A novel genetically engineered pathway for synthesis of poly(hydroxyalkanoic acids) in Escherichia coli. Applied and Environmental Microbiology, 66(2):739–743, February 2000.
- L.L. Madison and G.W. Huisman. Metabolic engineering of poly(3-hydroxyalkanoates): From DNA to plastic. Microbiology and Molecular Biology Reviews, 63(1):21–53, 1999.
- D.P. Martin and S.F. Williams. Medical applications of poly-4-hydroxybutyrate: a strong flexible absorbable biomaterial. Biochemical Engineering Journal, 16(2):97–105, 2003.
- E.F. Pettersen, T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin. UCSF Chimera — a visualization system for exploratory research and analysis. Journal of Computational Chemistry, 25(13):1605–1612, October 2004.
- S. Philip, T. Keshavarz, and I. Roy. Polyhydroxyalkanoates: biodegradable polymers with a range of applications. Journal of Chemical Technology & Biotechnology, 82(3):233–247, March 2007.
- Y. Poirier, D.E. Dennis, K. Klomparens, and C. Somerville. Polyhydroxybutyrate, a biodegradable thermoplastic, produced in transgenic plants. Science, 256(5056):520–523, April 1992.
- M. Pötter and A. Steinbüchel. Poly(3-hydroxybutyrate) granule-associated proteins: Impacts on poly(3-hydroxybutyrate) synthesis and degradation. Biomacromolecules, 6(2):552–560, 2005.
- S. Resch, K. Gruber, G. Wanner, S. Slater, D. Dennis, and W. Lubitz. Aqueous release and purification of poly(β-hydroxybutyrate) from Escherichia coli. Journal of Biotechnology, 65(2-3):173–182, October 1998.
- Y. Saito, S. Nakamura, M. Hiramitsu, and Y. Doi. Microbial synthesis and properties of poly(3-hydroxybutyrate-co-4-hydroxybutyrate): PHB and hydroxyalkanoate polymers. Polymer International, 39(3):169–174, 1996.
- J.A. Stubbe and J. Tian. Polyhydroxyalkanoate (PHA) homeostasis: the role of the PHA synthase. Natural Product Reports, 20:445–457, 2003.
- K. Sudesh, H. Abe, and Y. Doi. Synthesis, structure and properties of polyhydroxyalkanoates: biological polyesters. Progress in Polymer Science, 25(10):1503–1555, 2000.
- H.E. Valentin and D. Dennis. Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in recombinant Escherichia coli grown on glucose. Journal of Biotechnology, 58(1):33–38, October 1997.
- R.A.J. Verlinden, D.J. Hill, M.A. Kenward, C.D. Williams, and I. Radecka. Bacterial synthesis of biodegradable polyhydroxyalkanoates. Journal of Applied Microbiology, 102(6):1437–1449, 2007.
- W. Yuan, Y. Jia, J. Tian, K.D. Snell, U. Müh, A.J. Sinskey, R.H. Lambalot, C.T. Walsh, and J.A. Stubbe. Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and Allochromatium vinosum: Characterization and substrate specificity studies. Archives of Biochemistry and Biophysics, 394(1):87–98, October 2001.
- M. Zinn, B. Witholt, and T. Egli. Occurrence, synthesis and medical application of bacterial polyhydroxyalkanoate. Advanced Drug Delivery Reviews, 53:5–21, 2001.
Media sources
History
- PHA granules (1926 background)
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J.A. Stubbe and J. Tian. Polyhydroxyalkanoate (PHA) homeostasis: the role of the PHA synthase. Natural Product Reports, 20:445–457, 2003.
- Various monomers (1974 background)
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W. Yuan, Y. Jia, J. Tian, K.D. Snell, U. Müh, A.J. Sinskey, R.H. Lambalot, C.T. Walsh, and J.A. Stubbe. Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and Allochromatium vinosum: Characterization and substrate specificity studies. Archives of Biochemistry and Biophysics, 394(1):87–98, October 2001.
- Biosynthesis plasmid (1988 background)
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J. Kidwell, H.E. Valentin, and D. Dennis. Regulated expression of the Alcaligenes eutrophus PHA biosynthesis genes in Escherichia coli. Applied Environmental Microbiology, 61(4):1391–1398, April 1995.
- PHA synthase protein (2020 background)
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J.A. Stubbe and J. Tian. Polyhydroxyalkanoate (PHA) homeostasis: the role of the PHA synthase. Natural Product Reports, 20:445–457, 2003.
Our Vision
- Decomposing bioplastic bottles
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L.L. Madison and G.W. Huisman, “Metabolic engineering of poly(3-hydroxyalkanoates): from DNA to plastic”. Microbiology and Molecular Biology Reviews, 63(1):21–53, 1999.
Design
- PHA polymer at various magnification levels (edited)
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S.J. Liu and A. Steinbüchel, “Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly(hydroxyalkanoic acid)”. Applied Microbiology and Biotechnology, 53(5):545‒552, May 2000.
Impact
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Bliss
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by dezinerfolio (Flickr user navdeepraj), 19 May 2007licensed under the Creative Commons Attribution 2.0 License
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Rochester Factory
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by seraph_ben (Flickr user seraph), 4 December 2006licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 2.0 License
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Vondelpark Stork in Trash
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by -Andrew- (Flickr user americanidle), 5 July 2006licensed under the Creative Commons Attribution-NonCommercial 2.0 License
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50 years BUBBLE WRAP
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by Harald Schmid (Flickr user lf3180), 11 October 2007all rights reserved
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Sunny Side Up
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by code poet (Flickr user alphageek), 3 September 2006licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 2.0 License