When creating PACI we considered many different ideas for our design.

Molecular Structure of FDDNP

An MRI Machine

Alzheimer's Ribbon

Florbetapir vs. FDDNP
The biomarker that would safely and effectively bind to beta-amyloid plaques is florbetapir. The alternative choice was FDDNP, which also attaches to beta-amyloid plaques. However, FDDNP is not FDA approved and may cause harmful side effects. Florbetapir is a safer option proven to be effective.

PET vs. MRI
A PET scan is designed to use radioactive tracers to capture images, whereas an MRI machine uses magnetism. Unlike an MRI, only a PET scanner can utilize a tracer, thereby effectively capturing images of the brain using florbetapir.

Detection vs. Cure
Our team discussed whether to develop a cure for Alzheimer’s, or to create a machine to detect the disease before symptoms appear. Without a machine to diagnose Alzheimer's, there is insufficient knowledge about the disease to develop a cure. PACI would provide this information so that in the future, a cure can be developed.