- Growing Nephrons from Stem Cells:
- The growth factors of nephrons and kidney tissues must be discovered.
-We need a clear understanding of which growth factors affect the maturation of nephrons. - A matrix to sustain the kidney while it is developing needs to be created. -We will use adult derived stem cells, not embryonic stem cells. - More advanced stem cell research needs to take place.
- Tissue Cultures
- The tissue culturing process needs to be refined and made reliable. - Medium - A material that will sustain the growing organ needs to be discovered. - Developing a long lasting organ
- We want our organ to last for a patient's entire life so they will not have to
undergo multiple transplants. |
- Positive:
- Need for dialysis machines will be greatly reduced
(Required temporarily while kidneys are developing, not as a permanent solution)
- Will also eliminate the need for kidney donors - Reduce the number of deaths by kidney failure and raise the survival rate of patients suffering from a variety of kidney diseases
- Negative:
- More stem cell research on non-embryonic sources would be necessary
- Possible need for: - Injections of the hormone erythropoitein which regulates red blood cell production - Small doses of anti-rejection drugs (only if we do not use the patient's own cells) |