The human eye is a complex structure in which photoreceptors detect color, biological reactions turn light into electricity, and intermediate neurons transmit electrical signals.

Wet Macular Degeneration (left above) results from the leaking of abnormal blood vessels in the macula.
Characteristic of the Dry Macular Degeneration (left below) is the formation of drusen, which are believed to be fat deposits.

Retinitis Pigmentosa is a progressive genetic eye disorder in which the rods, cones, and retinal pigment epithelium are affected. Pigment clots form on the retina, leading to loss of peripheral vision and central vision during advanced stages.

Stargardt's Disease is an inherited eye disorder in which drusen spots form in the retina, causing the deterioration of photoreceptors and the macula.

Optic Nerve Hypoplasia is caused by the underdevelopment of the optic nerve in infants. The result can range from a decreased perception field to complete blindness. Because I-CEE is dependent upon the optic nerve for the transmission of the electrical signal, it is unable to cure or alleviate the symptoms of ONH.