A Combinatorial Approach to Breast Cancer Prognosis and Treatment Using Fractal Dimensional Analysis and Polymethyl Methacrylate (PMMA) Nanoparticles


Prognosis (Personalized MRA Tumor Detection Interface):

Based upon results of MRA (Magnetic Resonance Angiography) scans, the personalized computer interface is intended to improve the prognosis and identification of breast cancer in its early stages. The interface will use fractal dimensional analysis to analyze blood tissue architecture complexity in order to determine the extent of angiogenesis. The interface allows for the easy identification of which portions of the breast tissue to treat, providing for a minimally invasive and highly efficient procedure to determine the location of the primary tumor.

Treatment (Thermal Injection of PMMA Nanoparticles):

The thermal injection of polymethyl methacrylate (PMMA) nanoparticles at the site of the primary tumor is intended to target cancer-specific cells and reduce the size of the tumor. The thermal energy formed by the exothermic polymerization process in the PMMA nanoparticles will effectively "burn" the tumor cells, but not damage any healthy surrounding tissue cells. To prevent recurrences of breast cancer, the thermal effects of the PMMA nanoparticles will inhibit two molecules (TGF-beta & ANGPTL4) involved in metastasis.